We strongly recommend that you disable Adobe Creative Cloud when using Isadora with macOS – and probably whenever you're using any software that requires good real-time performance. The problems seem especially profound when using macOS High Sierra (v10.12.x)

Several Isadora users reported a severe slowdowns, sometimes experiencing frame rates of 5 fps or less when simply dragging a single actor. Upon investigating, we discovered that if the user logged out of Creative Cloud and quit the Creative Cloud application, performance returned to normal.

From what we can tell, this is not an Isadora specific problem. If you take a look at the links below, you'll see numerous  reports of serious system slowdowns in Adobe's user forums. There are also some solutions listed within these links, but most of them seem quite severe, e.g., reinstalling your system.

At the time of this writing, this seems to be a macOS specific problem. If we discover that there are similar problems on Windows, we will update this article.